John Silke Selected Research

Chromosomal Instability (Chromosome Stability)

1/2019

RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.

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John Silke Research Topics

Disease

35	Neoplasms (Cancer) 03/2024 - 06/2004
31	Inflammation (Inflammations) 01/2024 - 10/2000
12	Necrosis 01/2024 - 10/2000
10	Infections 01/2020 - 01/2010
7	Dermatitis 04/2024 - 03/2011
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2020 - 01/2016
3	Carcinogenesis 09/2021 - 11/2008
3	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 05/2014
2	2 X-Linked Lymphoproliferative Syndrome 01/2023 - 01/2017
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023 - 01/2017
2	Stomach Neoplasms (Stomach Cancer) 01/2022 - 11/2021
2	Leukemia 10/2020 - 12/2008
2	Lymphadenopathy 01/2020 - 01/2016
2	Hyperplasia 12/2015 - 10/2002
2	Wounds and Injuries (Trauma) 09/2015 - 07/2006
2	Multiple Myeloma 04/2011 - 03/2008
2	Brain Injuries (Brain Injury) 11/2008 - 07/2006
1	Residual Neoplasm 03/2024
1	Skin Diseases (Skin Disease) 01/2024
1	Mucositis 01/2023
1	Stomatitis 01/2023
1	Testicular Neoplasms (Testicular Cancer) 01/2023
1	COVID-19 01/2022
1	Airway Remodeling 01/2022
1	Emphysema 01/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2022
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Atrophy 10/2021
1	Thrombosis (Thrombus) 01/2021
1	Triple Negative Breast Neoplasms 10/2020
1	Breast Neoplasms (Breast Cancer) 10/2020
1	Fever (Fevers) 01/2020
1	Malaria 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2019
1	Genomic Instability 01/2019
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019
1	Anemia 01/2019
1	Chromosomal Instability (Chromosome Stability) 01/2019
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2018
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 11/2017
1	Carcinoma (Carcinomatosis) 01/2017
1	Brain Diseases (Brain Disorder) 01/2017
1	Bacterial Infections (Bacterial Infection) 01/2017

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 11/2020 - 03/2008
14	Phosphotransferases (Kinase)IBA 11/2023 - 01/2013
12	CytokinesIBA 01/2024 - 04/2014
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2021 - 11/2007
10	CaspasesIBA 01/2020 - 12/2008
9	birinapantIBA 10/2020 - 05/2014
8	Caspase 8 (Caspase-8)IBA 01/2023 - 01/2009
7	sharpinIBA 04/2024 - 03/2011
7	Inhibitor of Apoptosis ProteinsIBA 01/2020 - 04/2014
6	Type I Tumor Necrosis Factor ReceptorsIBA 11/2023 - 08/2013
5	UbiquitinIBA 10/2021 - 11/2008
4	AntigensIBA 01/2023 - 05/2015
4	Death Domain ReceptorsIBA 10/2020 - 09/2013
4	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 04/2014 - 03/2011
3	Protein Kinases (Protein Kinase)IBA 01/2019 - 03/2015
3	PerforinIBA 01/2019 - 10/2017
3	InterferonsIBA 01/2018 - 01/2017
3	TNF Receptor-Associated Factor 2 (TRAF2)IBA 01/2017 - 04/2011
3	Ligases (Synthetase)IBA 06/2012 - 05/2011
3	NF-kappa B (NF-kB)IBA 01/2010 - 11/2007
2	ChemokinesIBA 01/2024 - 01/2020
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2015
2	Surface Antigens (Surface Antigen)IBA 01/2020 - 05/2015
2	Granzymes (Granzyme)IBA 10/2017 - 10/2000
2	Cysteine Proteases (Cysteine Protease)IBA 02/2017 - 01/2017
2	Type III Secretion SystemsIBA 01/2017 - 09/2013
2	sphingosine kinaseIBA 01/2017 - 12/2015
2	AntibodiesIBA 09/2015 - 03/2008
2	Interleukin-33IBA 07/2015 - 05/2014
2	Carrier Proteins (Binding Protein)IBA 11/2008 - 07/2006
2	Caspase 9IBA 06/2004 - 10/2002
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2024
1	Hyaluronic Acid (Hyaluronan)IBA 01/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	Oxytocin Receptors (Oxytocin Receptor)IBA 01/2022
1	SmokeIBA 01/2022
1	B7-H1 AntigenIBA 11/2021
1	Transcription Factors (Transcription Factor)IBA 09/2021
1	Estrogen ReceptorsIBA 10/2020
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2020
1	Antimalarials (Antimalarial Agents)IBA 01/2020
1	Chimeric Antigen ReceptorsIBA 01/2019
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2018
1	DioxygenasesIBA 01/2018
1	Fas Ligand Protein (Fas Ligand)IBA 01/2018
1	Cysteamine (Mercaptamine)FDA Link 01/2018
1	EkoIBA 11/2017
1	Poly I-CIBA 01/2017
1	LCL161IBA 01/2017
1	LipopolysaccharidesIBA 01/2017

Therapy/Procedure

7	Therapeutics 03/2024 - 05/2015
4	Immunotherapy 12/2021 - 01/2018
3	Drug Therapy (Chemotherapy) 01/2023 - 01/2016
1	Radiotherapy 01/2023
1	Braces 01/2020